News Releases

SURPRISE, Ariz., June 25, 2025 – SenesTech, Inc. (NASDAQ: SNES, "SenesTech" or the "Company"), a leader in fertility control for managing animal pest populations, today announce a nine-month field trial of Evolve™ Rat Birth Control at the University Hills (UHills) residential community at the University of California, Irvine. The project was conducted in partnership with the Irvine Campus Housing Authority (ICHA), the nonprofit corporation that manages University Hills, and reflects a growing commitment to ecologically responsible pest management.

The initiative began in September 2024 and marked the exclusive use of Evolve Rat Birth Control across common areas of the UHills community. This deployment was part of a broader effort supported by residents interested in moving away from rodenticides in favor of integrated pest management (IPM) strategies that prioritize environmental safety and wildlife preservation. Located adjacent to a wildlife reserve, the community's shift away from rodenticides further supports the protection of local wildlife and ecosystems.

“This project highlights how community-driven action and science-based solutions can work together to support sustainability,” said Joel Fruendt, President and CEO of SenesTech. “Evolve aligns with these goals by providing a non-lethal, poison-free solution to rodent control.”

Evolve was deployed across 267 bait stations previously containing rodenticides and snap traps. According to field observations, rats consumed 98% of Evolve across all stations each month, indicating high acceptance and performance of the bait. As expected, consumption dropped as the rat population dropped.

The field trial also supported the efforts of the HOOT Group (Help Our Owls Thrive), a grassroots initiative formed by UHills residents to promote owl nesting and reduce rodenticide use. Together, the partners implemented a range of actions, including installation of enclosed snap traps, removal of rodent harborage areas, and installation of barn owl nesting boxes to encourage natural predation.

“The partnering with SenesTech in utilizing Evolve has supported ICHA’s and the UHills community’s heightened focus on IPM sensitivity to the local wildlife and raptor population,” said Andrew Herndon, Vice President of Community Development at ICHA. “Evolve appears to offer a reduction of poisons in the environment while at the same time a reduction of the rodent population.”

As a result of the collaboration, rodenticides have been eliminated from all 267 bait stations across common areas in UHills. SenesTech is pleased to contribute to this transition and to support communities like UHills and organizations like ICHA and HOOT that are leading the way in redefining effective, responsible rodent control.

ICHA plans to continue using Evolve in University Hills.

About SenesTech
We are committed to improving the health of the world by humanely managing animal pest populations through our expertise in fertility control. We invented ContraPest^®, the only U.S. EPA-registered contraceptive for male and female rats, as well as Evolve™ Rat and Evolve™ Mouse, EPA-designated minimum risk contraceptives for rodents, reflecting our mission to provide products that are proactive, safe and sustainable. ContraPest and Evolve fit seamlessly into all integrated pest management programs, significantly improving the overall goal of effective pest management. We strive for clean cities, efficient businesses and happy households – with a product designed to be humane, effective and sustainable.

For more information visit https://senestech.com/.

Safe Harbor Statement
This press release contains “forward-looking statements” within the meaning of federal securities laws, and we intend that such forward-looking statements be subject to the safe harbor created thereby. Such forward-looking statements include, among others, our belief that the UHills project reflects a growing commitment to ecologically responsible pest management; our belief that this project highlights how community-driven action and science-based solutions can work together to support sustainability; and our expectation for a multi-pallet restocking order for continued deployment. Forward-looking statements may describe future expectations, plans, results or strategies and are often, but not always, made through the use of words such as “believe,” “may,” “future,” “plan,” “will,” “should,” “expect,” “anticipate,” “eventually,” “project,” “estimate,” “continuing,” “intend” and similar words or phrases. You are cautioned that such statements are subject to risks, uncertainties and other factors that could cause actual results to differ materially from those reflected by such forward-looking statements. Such factors include, among others, the successful commercialization of our products, market acceptance of our products, regulatory approval and regulation of our products and other factors and risks identified from time to time in our filings with the Securities and Exchange Commission, including our Annual Report on Form 10-K for the fiscal year ended December 31, 2024. All forward-looking statements contained in this press release speak only as of the date on which they were made and are based on management's assumptions and estimates as of such date. Except as required by law, we do not undertake any obligation to publicly update any forward-looking statements, whether as a result of the receipt of new information, the occurrence of future events or otherwise.

Contact Information:
Investors:
Robert Blum, Lytham Partners, LLC
(602) 889-9700
senestech@lythampartners.com

Marketing:
Rochelle Paulet, Director of Marketing, SenesTech, Inc.
(928) 779-4143 x814

SOURCE SenesTech, Inc.